TUSI Valve: Echocardiographic and Pathologic Correlates of a Novel Drug-Induced Valvular Disease-a Case Series.
Juan Felipe Vasquez-Rodriguez, Gustavo Lemus-Barrios, Diego Rangel-Rivera, Valentina Garnica-Sepulveda, Yeisson Avila, Ramon Medina-Mur, Oscar M Perez-Fernandez, Diego Holguín-riaño, Gabriel Salazar-Castro, Karen Dueñas-criado
CASE April 1, 2026 DOI: 10.1016/j.case.2026.01.003 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Case report Peer reviewed |
|---|---|
| Keywords | 3,4-methylenedioxymethamphetamine Echocardiography Heart valve diseases Tusi |
| Key findings | TUSI use may cause serotonin-mediated drug-induced valvular disease, with echocardiographic thickening and restricted atrioventricular valve motion and histological myxoid degeneration. |
Abstract
• TUSI ("pink cocaine") use may cause serotonin-mediated drug-induced valvular disease. • Echocardiography shows reproducible thickening and restricted atrioventricular valve motion. • Histology reveals myxoid degeneration without inflammatory infiltrate. • Young patients with unexplained regurgitation require drug-use screening. • Synthetic drug use poses emerging cardiovascular risks needing attention.
Citations in the library
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