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Epidemiology and Psychiatric Sciences

ISSN 2045-7960

2 papers in the library · 32 citations · publishing 2023-2026

Papers

Phenomenology as a resource for translational research in mental health: methodological trends, challenges and new directions.

Epidemiology and Psychiatric Sciences January 16, 2023 R Ritunnano, D Papola, M R Broome et al. 32 citations

Translational mental health research should bridge interventional and phenomenologically informed approaches. Phenomenological insights into schizophrenia and psychosis have improved prediction, diagnosis, and treatment, and qualitative studies have revealed complex subjective dimensions of delusions and hallucinations that quantitative methods miss. Despite these advances, integrating phenomenological findings into clinical research remains limited. The authors argue that phenomenological psychopathology, as psychiatry's basic science, is essential for evidence-based practices and meaningful patient outcomes. Advancing this requires prioritizing subjectivity, patient-centred outcome measures, and treatment targets that matter to patients.

Ketamine treatment alleviates suicide ideation in high-risk populations: a systematic review and meta-analysis

Epidemiology and Psychiatric Sciences January 1, 2026 Wen Tang, Wei-Wei Jiang, Wen-Qian Que et al.

Ketamine treatment significantly reduces suicide ideation in high-risk individuals, with a large effect size of -1.40 based on a meta-analysis of 21 studies involving 927 participants. The effect is more pronounced in younger individuals and those with severe ideation. Common adverse events include dissociation (38.8%), nausea (31.6%), dizziness (24.7%), headache (22.0%), and anxiety (15.8%). The evidence is rated low quality, and further research is needed to determine optimal dosing and long-term effects.