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Pharmacology and Toxicology of Natural Medicines

ISSN 2756-6838

2 papers in the library · publishing 2026

Papers

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Syringic Acid Prevents and Reverses Ketamine-induced Schizophrenia-like Memory Impairment

Pharmacology and Toxicology of Natural Medicines October 31, 2026 Benneth Ben-Azu, Joseph O.T Emudainohwo, Bienose S Chijioke et al.

Background and Purpose: Alterations in the cholinergic-inflammatory pathway are believed to play a role in the cognitive symptoms of schizophrenia, a common neuropsychiatric condition characterised by altered perceptions of reality and impairments in learning and memory. In this study, we examined the preventive and reversal effects of syringic acid (SA), a naturally occurring phenolic...

Neuroprotective Effect of Jobelyn® on Ketamine-Induced Schizophrenia-Like Behaviors and Oxidative Damage in Mice Brain

Pharmacology and Toxicology of Natural Medicines July 7, 2026 Itivere Adrian Omogbiya, Benneth Ben-Azu, Maxwell Oboh et al.

Background and Purpose: Schizophrenia is a chronic, debilitating psychiatric disorder affecting many young adult populations worldwide. Evidence from studies of central changes in the oxidative defense system suggests the involvement of oxidative stress in the pathophysiology of schizophrenia. Jobelyn® (JB) is a commercial polyherbal formulation that has been documented to show beneficial...

DOI: 10.52406/ptnm.v6i4.176 (opens in new tab) Oxidative stress Neuroprotection Tbars Superoxide dismutase +9