Biochemical Journal
June 15, 2011
Zoë Barclay, Louise Dickson, Derek N Robertson et al.
The 5-HT2AR (5-hydroxytryptamine-2A receptor) is a GPCR (G-protein-coupled receptor) that is implicated in the actions of hallucinogens and represents a major target of atypical antipsychotic agents. In addition to its classical signalling though PLC (phospholipase C), the receptor can activate several other pathways, including ARF (ADP-ribosylation factor)-dependent activation of PLD...
Biochemical Journal
November 1, 1971
R. K. Datta, W. Antopol, Jagat J. Ghosh
8 citations
1. The effect of spermidine on the mescaline-induced changes of brain-cortex ribosomes was studied by adding spermidine during the treatment of goat brain-cortex slices with mescaline. 2. Mescaline treatment of brain-cortex slices removed a portion of the endogenous spermidine from ribosomes and this removal was significantly prevented when spermidine was present during mescaline treatment. 3....
Biochemical Journal
May 1, 1970
R. K. Datta, Jagat J. Ghosh
12 citations
1. During the action of mescaline sulphate on goat brain-cortex slices the ribosomal particles become susceptible to breakdown, releasing protein, RNA, acidsoluble nucleotides and ninhydrin-positive materials, resulting in loss of ribosomal enzyme activities. 2. Ribosomes of the mescaline-treated cortex slices undergo rapid degradation in the presence of trypsin and ribonuclease. 3. Mescaline...
Biochemical Journal
May 1, 1970
R. K. Datta, Jagat J. Ghosh
8 citations
1. The action of mescaline sulphate on the hydrogen-bonded structure of the RNA constituent of ribosomes of goat brain-cortex slices was studied by using the hyperchromic effect of heating and formaldehyde reaction. 2. The ribosomal total RNA species of the mescaline-treated brain-cortex slices have a smaller proportion of hydrogen-bonded structure than the ribosomal RNA species of the...
Biochemical Journal
August 1, 1954
Joyce L. Lewis, H. Mcilwain
29 citations
Research Article| August 01 1954 The action of some ergot derivatives, mescaline and dibenamine on the metabolism of separated mammalian cerebral tissues Joyce L. Lewis; Joyce L. Lewis 1Department of Biochemistry, Institute of Psychiatry (British Postgraduate Medical Federation, University of London), Maudsley Hospital, S.E. 5 Search for other works by this author on: This Site PubMed Google...