Cancer
June 15, 2025
Manish Agrawal, Kim Roddy, Betsy Jenkins et al.
4 citations
Abstract Background Patients with cancer often struggle with depression, which can negatively impact quality of life as well as be challenging to manage. Methods A phase 2 trial was conducted that demonstrated safety, feasibility, and efficacy of a single dose of psilocybin combined with psychological support in a community cancer setting in 30 patients with cancer and a major depressive...
Cancer
December 18, 2023
Manish Agrawal, Yvan Beaussant, Sarah Shnayder et al.
73 citations
Abstract Background Depression is common in patients with cancer and is associated with lower treatment adherence and reduced quality of life. Antidepressants and psychotherapy have limited success in improving depression among patients with cancer. This study explored the safety, feasibility, and efficacy of psilocybin‐assisted therapy in patients with cancer and major depressive disorder....
Cancer
December 18, 2023
Yvan Beaussant, Kabir Nigam, Zachary Sager et al.
22 citations
Abstract Background The present study explored the acceptability of psilocybin‐assisted group therapy from the perspective of patients with cancer and depression who participated in a clinical trial assessing the safety and efficacy of this novel intervention. Methods Guided by the conceptual framework of acceptability, the authors conducted semi‐structured interviews with participants of the...
Cancer
December 18, 2023
Johannes Thrul, Zofia Kozak, Michael A. Carducci et al.
5 citations
Several recent studies have investigated psilocybin as a novel therapeutic compound for the treatment of existential distress in patients with cancer, demonstrating persistent, positive effects on mood. This editorial discusses two articles in the current issue of Cancer that report findings of a group‐based psilocybin‐assisted intervention for treatment of depression in patients diagnosed with...
Cancer
April 6, 2022
Alicia Duval, Christopher G. Davis, Eve-Ling Khoo et al.
Breast cancer (BC) survivors frequently report changes in cognition after chemotherapy. Mindfulness may benefit survivors by mitigating cancer‐related cognitive impairment. As part of a larger study investigating the effects of mindfulness‐based stress reduction (MBSR) for BC survivors living with neuropathic pain, the authors assessed whether MBSR would have an effect on cognitive outcomes.