Human & Experimental Toxicology
March 11, 2025
Tharuka Wijesekara, Baojun Xu
5 citations
Introduction Mushrooms, belonging to the phyla Ascomycota and Basidiomycota, comprise approximately 14,000 known species, among which a small fraction are toxic. While toxic mushrooms are primarily associated with adverse health effects, recent research highlights their potential as sources of bioactive compounds with promising therapeutic applications. Methods A systematic review was conducted...
Human & Experimental Toxicology
November 25, 2018
H. Jiang, H. Xu
Retracted
As a classical hallucinogen with high potential for abuse, lysergic acid diethylamide (LSD) can cause long-lasting abnormalities in retina, but little is known about the exact mechanism. This study was to investigate effects of long-term systemic treatment of LSD at low dose on retinal damage and understand the underlying mechanisms. CD1 mice were treated intraperitoneally with 0.1 mg/kg or 0.2...
Human & Experimental Toxicology
May 20, 2010
Pinchas Halpern, Jenny Moskovich, Beni Avrahami et al.
54 citations
Methods: We conducted a prospective, representative-sample nationwide study on morbidity related to 3,4, methylenedioxymethamphetamine (MDMA; ‘ecstasy’) as determined from admissions to 5 geographically representative emergency departments (EDs) and from data from the poison information center (PIC). MDMArelated ED admissions were analyzed over a 7-month period and the records of all PIC calls...
Human & Experimental Toxicology
March 1, 2008
R Maciulaitis, Violeta Kontrimaviciūte, Françoise M M Bressolle et al.
102 citations
Ibogaine is an indole alkaloid derived from the bark of the root of the African shrub Tabernanthe iboga. Psychoactive properties of ibogaine have been known for decades. More recently, based on experimental data from animals and anectodal reports in human, it has been found that this drug has anti-addictive effects. Several patents were published between 1969 and 1995. The pharmacology of...
Human & Experimental Toxicology
June 2002
M Mulheran, P Middleton, J A Henry
The study was designed to investigate the acute effects of ingested tetrahydrocannabinol (THC) on auditory function. Eight male subjects (aged 22-30 years), who had previous experience of cannabis use, took part in this study. They performed air conduction pure tone audiometry in both ears over 0.5-8 kHz. A simple test of frequency selectivity by detecting a 4-kHz tone under two masking noise...
Human & Experimental Toxicology
February 1, 1999
Andrew Walubo, Donna Seger
73 citations
A 53-year-old prisoner died of multiorgan failure after a suicidal overdose with 3,4-methylenedeoxymethamphe-tamine (MDMA, `Ecstasy'). Twelve hours after ingestion of MDMA, the patient became severely hyperthermic (107.2°F) with evidence of rhabdomyolysis. He subsequently developed acute respiratory distress syndrome (ARDS), disseminated intravascular coagulopathy (DIC) and acute renal failure....