Neurogastroenterology and motility

Endocannabinoid signaling in stress, nausea, and vomiting.

Neurogastroenterology and motility March 2025 Marieka V DeVuono, Thangam Venkatesan, Cecilia J. Hillard

Classical antiemetics that target the serotonin system may not be effective in treating certain nausea and vomiting conditions like cyclic vomiting syndrome (CVS) and cannabinoid hyperemesis syndrome (CHS). As a result, there is a need for better therapies to manage the symptoms of these disorders, including nausea, vomiting, and anxiety. Cannabis is often used for its purported antiemetic and...