Clinical Neurophysiology Practice

ISSN 2467-981X

2 papers in the library · publishing 2026

Papers

Effects of transcranial direct current stimulation and mindful walking on directional brain connectivity: An isolated effective coherence analysis

Clinical Neurophysiology Practice January 1, 2026 Keiichiro Nishida, Naoya Onishi, Yosuke Koshikawa et al.

Combining anodal transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex with treadmill walking for focused mindfulness alters brain connectivity in ways that may reduce default mode network dominance and strengthen executive control. In 77 healthy participants, active tDCS reduced information flow from the posterior cingulate cortex to the rostral anterior cingulate cortex within the default mode network, while mindfulness reduced flow from the rostral anterior cingulate cortex to the medial prefrontal cortex. Active tDCS strengthened interhemispheric executive control network connectivity. The combined intervention produced hierarchical decoupling of the default mode network, suggesting potential for facilitating mindfulness engagement.

DOI: 10.1016/j.cnp.2026.07.006 Transcranial direct-current stimulation Direct current Brain stimulation Current fluid +4

Regional and cannabis-related differences in prefrontal multiscale entropy of resting-state EEG.

Clinical Neurophysiology Practice January 1, 2026 William T Creel, Colleen A Brenner, Richard E Hartman

Frequent cannabis use is associated with reduced neural signal complexity in the prefrontal cortex, as measured by multiscale entropy (MSE) of resting-state EEG. In 57 adults—non-users, low-frequency users (≤1x/week), and frequent users (≥2x/week)—MSE increased with coarser temporal scales in all groups, but the slope was significantly flatter in frequent users. From medium to very-coarse scales, their prefrontal entropy slope was 0.12 to 0.16 bits lower than non-users. Across all participants, the prefrontal cortex showed lower MSE than parietal, occipital, and temporal lobes, with larger differences at coarser scales. MSE detects cannabis-related reductions in prefrontal signal complexity at longer temporal scales.

DOI: 10.1016/j.cnp.2026.02.003 Full text Cannabis Electroencephalography Entropy Neurophysiology +1