OBJECTIVE A systematic review was conducted to synthesize current anatomo-clinical correlations of ecstatic symptoms in focal epilepsy, aiming to provide evidence-based guidance for interpreting this ictal semiology during presurgical evaluation. METHODS We searched PubMed and Web of Science using terms related to ecstatic experience (e.g., ecstatic, bliss, mystical, time dilation) combined...
Epileptic DisordersJune 21, 2025Ionuț-Flavius Bratu, Nada El Youssef, Stanislas Lagarde et al.5 citations
Loss of consciousness/awareness during temporal lobe seizures significantly affects quality of life and is closely linked to pathological thalamocortical synchronization and loss of cortical signal complexity. The medial pulvinar nucleus (PUM) contributes to seizure propagation and awareness impairment, making it a potential target for neuromodulation. Acute high-frequency PUM stimulation has...
We performed a systematic review of the localizational value of disturbances of self-integration, depersonalization and forced thinking in focal epilepsy with the aim to summarize the state-of-the-art anatomo-clinical correlations in the field and help guide interpretation of ictal semiology within the framework of pre-surgical evaluation. The review was performed using a PRISMA- and...