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Int J Mol Sci

ISSN 1422-0067

2 papers in the library · 4 citations · publishing 2025

Papers

Salvinorin A and Salvia divinorum: Toxicology, Pharmacological Profile, and Therapeutic Potential.

Int J Mol Sci June 11, 2025 4 citations

Salvia divinorum is a psychoactive plant with a complex pharmacological profile that has attracted scientific interest for both its potential therapeutic applications and associated health risks. This review analyzes the toxic and therapeutic effects of S. divinorum, evaluating its possible medical uses while highlighting consumption risks. It also examines the plant's recreational use, global consumption trends, and legal status. The article synthesizes current research to clarify the implications of S. divinorum use and inform future studies on its pharmacological potential and regulatory considerations.

DOI: 10.3390/ijms26125588 (opens in new tab) Full text (opens in new tab) Salvinorin a Salvia divinorum Natural compound Unique compound +17

Sublethal Concentrations of 2C-I and 25I-NBOMe Designer Drugs Impact Caenorhabditis elegans Development and Reproductive Behavior.

Int J Mol Sci March 26, 2025 Eva Gil-Martins, Daniel José Barbosa, Fernando Cagide et al.

Sublethal concentrations of the designer drugs 2C-I and 25I-NBOMe impair development and reproductive behavior in the roundworm Caenorhabditis elegans. Exposed worms showed delayed growth and altered egg-laying patterns, indicating that even low, non-lethal doses of these substances can disrupt key biological processes. The findings suggest potential developmental and reproductive risks from these drugs.

DOI: 10.3390/ijms26073039 (opens in new tab) Full text (opens in new tab) Designer drugs C. elegans Biological effects