Addiction
February 20, 2003
Erkki Vuori, John A. Henry, Ilkka Ojanperä et al.
113 citations
ABSTRACT Four deaths following the ingestion of moclobemide and MDMA (‘ecstasy’) are described. The probable cause of death in each case was serotonin syndrome as a result of an interaction between the two drugs. As none of the victims had been prescribed moclobemide it seems that each had taken the drug to enhance the effects of MDMA, with fatal consequences. Warnings are needed against...
Addiction
December 1, 2002
Jon C. Cole, Mike Bailey, Harry Sumnall et al.
149 citations
ABSTRACT Aims To examine the variation in the content of ecstasy tablets seized in the north‐west of England during 2001 and to compare it to the UK average from 1991 to 2001. Measurements All tablets submitted to the Forensic Science Service in the north‐west of England during 2001 were analysed by high performance liquid chromatography with diode array detection (HPLC‐DAD). The mean MDMA...
Addiction
November 1, 2001
Mitch Earleywine
57 citations
AIMS: Koro, an acute panic reaction related to the perception of penile retraction, was once considered limited to specific cultures. The disorder has appeared as part of a panic response to cannabis, but only in citizens of India. This study looked for cannabis-induced Koro in Americans. DESIGN: Given the relative rarity of cannabis-induced Koro, this work focused on individual case studies....
Addiction
July 1, 2001
Sarah Riley, Charlotte James, Danielle Gregory et al.
172 citations
Aims . To describe the patterns of drug use at dance (rave) events in terms of prevalence, frequency, type of drugs used, patterns of use, access and risk‐associated behaviours. Design . Self‐selecting participant‐completed survey. Setting . Three dance events in Edinburgh, Scotland, UK. Participants . One hundred and twenty‐two drug users (57% males, 43% females), 90% of whom were in...
Addiction
May 1, 2001
H. Valerie Curran, Lisa Monaghan
Aims. Ketamine, a non‐competitive NMDA receptor antagonist, produces acute impairments of working, episodic and semantic memory along with psychotogenic and dissociative effects when a single dose is given to healthy volunteers. In recreational users, Curran & Morgan (2000) showed that ketamine produced the same acute effects but that 3 days after ingestion, ketamine users showed persisting...
Addiction
July 1, 1997
Valerie H. Curran, Ross A. Travill
283 citations
Abstract Aims. Recreational use of ± 3,4‐methylenedioxymethamphetamine (MDMA, ‘ecstasy’) is widespread. The present study aimed to examine both the acute and residual effects of this drug on users' mood and cognitive Junction. Design and participants. A parallel group design was used to compare 12 participants who reported having taken MDMA with 12 participants who reported having consumed only...
Addiction
June 1, 1994
LSD and post-hallucinogen perceptual disorder.
Addiction
May 1, 1994
Thomas Steele, Una D. Mccann, George A. Ricaurte
295 citations
Abstract (±)3,4‐Methylenedioxymethamphetamine (MDMA, “Ecstasy”), a ring‐substituted amphetamine derivative first synthesized in 1914, has emerged as a popular recreational drug of abuse over the last decade. Pharmacological studies indicate that MDMA produces a mixture of central stimulant and psychedelic effects, many of which appear to be mediated by brain monoamines, particularly serotonin...
Addiction
October 1, 1993
Henry David Abraham, Andrew M. Aldridge
140 citations
Abstract The continued endemic use of hallucinogenic drugs, and of LSD in particular, raises concern regarding their short and long term adverse consequences. The epidemiology of LSD abuse is reviewed suggesting an increase in LSD use among the young as the prevalence rates for other substances continues to fall. Evidence supports the association of LSD use with panic reactions, prolonged...