Ketamine for the treatment of major depression: a systematic review and meta-analysis
EClinicalMedicine August 1, 2023 Stevan Nikolin, Anthony Rodgers, Andreas Schwaab et al. 166 citations
Background: Intranasal esketamine has received regulatory approvals for the treatment of depression. Recently a large trial of repeated dose racemic ketamine also demonstrated efficacy in severe depression. However, uncertainties remain regarding comparative efficacy, dosage, and the time course of response. Methods: In this systematic review and meta-analysis, we searched Embase, Medline,...