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Holim Lee

1 paper in the library · 150 citations · publishing 2022

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Ketamine treatment for depression: a review

Discover Mental Health April 15, 2022 Mani Yavi, Holim Lee, Ioline D. Henter et al. 150 citations

-enantiomer, intranasal esketamine, for the treatment of major depressive disorder (MDD). Initial studies found that a single subanesthetic-dose IV ketamine infusion rapidly (within one day) improved depressive symptoms in individuals with MDD and bipolar depression, with antidepressant effects lasting three to seven days. In 2019, esketamine received FDA approval as an adjunctive treatment for...