Lifetime Psychedelic Use and Opioid Use Disorder Severity: Substance-Use Pattern Specific and Mental Health–Dependent Associations in a National Survey
PsyArXiv November 2, 2025 Sebastian Ehmann, Nathan M. Hager, Paul S. Regier et al. preprint
Background and AimsThe ongoing opioid epidemic remains a major public health crisis in the United States, with over 100,000 opioid-related deaths annually. Mental health disorders are strongly associated with opioid use disorder (OUD), compounding risks of misuse and overdose. Emerging evidence indicates that psychedelics may be associated with reduced risk of OUD. This study aimed to estimate...
DOI: 10.31234/osf.io/jd2rk_v1 (opens in new tab)
Opioid use disorder
Substance use disorder
Psychedelics
Psychedelic use
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