5 papers in the library · 1,973 citations · publishing 2010-2021
Front Pharmacol March 25, 2021 Hannes Kettner, Fernando E. Rosas, C. Timmermann et al. 205 citations
Psychedelic Communitas: Intersubjective Experience During Psychedelic Group Sessions Predicts Enduring Changes in Psychological Wellbeing and Social Connectedness.
Psychopharmacology (Berl) November 8, 2017 R. L. Carhart-Harris, Mark Bolstridge, C. M. J. Day et al. 978 citations
RATIONALE: Recent clinical trials are reporting marked improvements in mental health outcomes with psychedelic drug-assisted psychotherapy. OBJECTIVES: Here, we report on safety and efficacy outcomes for up to 6 months in an open-label trial of psilocybin for treatment-resistant depression. METHODS: Twenty patients (six females) with (mostly) severe, unipolar, treatment-resistant major...
Psychopharmacology October 30, 2017 J. B. Stroud, Tom P. Freeman, Robert Leech et al. 102 citations
RATIONALE: Depressed patients robustly exhibit affective biases in emotional processing which are altered by SSRIs and predict clinical outcome. OBJECTIVES: The objective of this study is to investigate whether psilocybin, recently shown to rapidly improve mood in treatment-resistant depression (TRD), alters patients' emotional processing biases. METHODS: Seventeen patients with...
Journal of Substance Use July 30, 2010 R. L. Carhart-Harris, D. J. Nutt 108 citations
This study used a web-based questionnaire to investigate user perceptions of the benefits and harms of hallucinogenic drug use. Over 600 forms were submitted. Users were asked to comment on the acute and prolonged effects of different drugs and to provide more specific information on how particular drugs have harmed and/or helped them. Subjects reported relatively less harm associated with the...
Brain February 28, 2010 R. L. Carhart-Harris, K. J. Friston 580 citations
This article explores the notion that Freudian constructs may have neurobiological substrates. Specifically, we propose that Freud's descriptions of the primary and secondary processes are consistent with self-organized activity in hierarchical cortical systems and that his descriptions of the ego are consistent with the functions of the default-mode and its reciprocal exchanges with...