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Paul M. Vespa

3 papers in the library · 151 citations · publishing 2021-2025

Papers

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AI Discovery of Mechanisms of Consciousness, Its Disorders, and Their Treatment

Research Square July 8, 2025 Daniel Toker, Zhong Zheng, Jasmine Thum et al. preprint

Abstract Understanding disorders of consciousness (DOC) remains one of the most challenging problems in neuroscience, hindered by the lack of experimental models for probing mechanisms or testing interventions. To address this, we introduce a generative adversarial AI framework that pits deep neural networks—trained to detect consciousness across over 680,000 neuroelectrophysiology samples and...

Consciousness is supported by near-critical slow cortical electrodynamics.

Proceedings of the National Academy of Sciences February 1, 2022 Daniel Toker, Ioannis Pappas, Janna D. Lendner et al. 148 citations

Mounting evidence suggests that during conscious states, the electrodynamics of the cortex are poised near a critical point or phase transition and that this near-critical behavior supports the vast flow of information through cortical networks during conscious states. Here, we empirically identify a mathematically specific critical point near which waking cortical oscillatory dynamics operate,...

DOI: 10.1073/pnas.2024455119 (opens in new tab) Full text (opens in new tab) Consciousness Awareness Sentience Perception +11

Consciousness is supported by near-critical cortical electrodynamics

bioRxiv June 11, 2021 Daniel Toker, Ioannis Pappas, Janna D. Lendner et al. 3 citations preprint

Mounting evidence suggests that during conscious states, the electrodynamics of the cortex are poised near a critical point or phase transition, and that this near-critical behavior supports the vast flow of information through cortical networks during conscious states. Here, for the first time, we empirically identify the specific critical point near which conscious cortical dynamics operate...

DOI: 10.1101/2021.06.10.447959 (opens in new tab) Consciousness Conscious experience Conscious states Awareness state +16