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G. Williams

3 papers in the library · 35 citations · publishing 2011-2022

Papers

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Whole-brain modelling identifies distinct but convergent paths to unconsciousness in anaesthesia and disorders of consciousness

Communications Biology April 20, 2022 Andrea I. Luppi, Pedro A. M. Mediano, Fernando E. Rosas et al.

The human brain entertains rich spatiotemporal dynamics, which are drastically reconfigured when consciousness is lost due to anaesthesia or disorders of consciousness (DOC). Here, we sought to identify the neurobiological mechanisms that explain how transient pharmacological intervention and chronic neuroanatomical injury can lead to common reconfigurations of neural activity. We developed and...

Fractal Dimension of Cortical Functional Connectivity Networks Predicts Severity in Disorders of Consciousness

bioRxiv Preprint Server October 1, 2019 Tf. Varley, M. Craig, Ram Adapa et al. preprint

Recent evidence suggests that the quantity and quality of conscious experience may be a function of the complexity of activity in the brain, and that consciousness emerges in a critical zone on the axes of order/randomness and integration/differentiation. We propose fractal shapes as a measure of proximity to this critical point, as fractal dimension encodes information about complexity beyond...

Consciousness, Plasticity, and Connectomics: The Role of Intersubjectivity in Human Cognition

Frontiers in Psychology 2011 Micah Allen, G. Williams 35 citations

Consciousness is typically construed as being explainable purely in terms of either private, raw feels or higher-order, reflective representations. In contrast to this false dichotomy, we propose a new view of consciousness as an interactive, plastic phenomenon open to sociocultural influence. We take up our account of consciousness from the observation of radical cortical neuroplasticity in...