Exploring Neural Dynamics in Self-Voice Processing and Perception: Implications for Hallucination Proneness
bioRxiv (Cold Spring Harbor Laboratory) September 22, 2023 Suvarnalata Xanthate Duggirala, Hanna Honcamp, Michael Schwartze et al. 1 citation preprint
Auditory verbal hallucinations occur along a continuum from the general population to patients with psychosis, yet how sensory feedback processing and attention control interact along this continuum is unclear. By manipulating self-voice quality (from neutral to angry) and measuring brain activity with electroencephalography, the study found that hallucination proneness (HP) modulated the N100 and P200 suppression effects regardless of voice quality. Individuals with high HP showed an increased N100 response to self-generated voices and an increased P200 response to externally-generated voices, suggesting heightened error awareness and attention allocation during self-voice production due to altered sensory feedback processing and attentional control. These findings indicate that altered sensory feedback processing in self-voice production is a fundamental characteristic of the HP continuum, independent of clinical status.