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Lennart R.b. Spindler

2 papers in the library · publishing 2021

Papers

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Dopaminergic brainstem disconnection is common to pharmacological and pathological consciousness perturbation

Proceedings of the National Academy of Sciences of the United States of America July 23, 2021 Lennart R.b. Spindler, Andrea I. Luppi, Ram Adapa et al.

Significance Understanding the neural bases of consciousness is of basic scientific and clinical importance. Human neuroimaging has established that a network of interconnected brain regions known as the default mode network disintegrates in anesthesia and after brain damage that causes disorders of consciousness. However, the neurochemical underpinnings of this network change remain largely...

Network dynamics scale with levels of awareness

bioRxiv Preprint Server April 12, 2021 Peter Coppola, Lennart R.b. Spindler, Andrea I. Luppi et al. preprint

Small world topologies are thought to provide a valuable insight into human brain organisation and consciousness. However, functional magnetic resonance imaging studies in consciousness have not yielded consistent results. Given the importance of dynamics for both consciousness and cognition, here we investigate how the diversity of brain dynamics pertaining to small world topology (quantified...