Ketamine: Neuroprotective or Neurotoxic?
Frontiers in Neuroscience September 10, 2021 Divya Choudhury, Anita E. Autry, K. Tolias et al. 75 citations
Ketamine, a non-competitive N-methyl-D-aspartate receptor (NMDAR) antagonist, has been employed clinically as an intravenous anesthetic since the 1970s. More recently, ketamine has received attention for its rapid antidepressant effects and is actively being explored as a treatment for a wide range of neuropsychiatric syndromes. In model systems, ketamine appears to display a combination of...