Ketamine's Role in Neuroinflammation and Neuroprotection Across Neurological and Psychiatric Disorders: A Narrative Review.
Pharmaceuticals August 29, 2025 Gustavo N Silva, Virna G A Brandão, Kenneth Blum et al. 7 citations
Ketamine, a widely used anesthetic with emerging evidence suggesting neuroprotective and anti-inflammatory properties across various neurological disorders, is recognized for its NMDA receptor antagonism. It has been postulated to play a role in neuroprotection, due to its anti-inflammatory properties, and decrease microglial activation, as well as cytokines TNF and IL-6. Despite its...
DOI: 10.3390/ph18091298 (opens in new tab)
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Nmda receptors
Brain injury
Ketamine ketamine
Neuroprotection neuroprotection
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