Δ9-tetrahydrocannabinol (THC) is responsible for the intoxicating (psychotropic) effects of cannabis and cannabis-derived products currently available in the legal and illegal markets. The psychotropic effects of THC are produced via activation of CB1 cannabinoid receptors in the brain, which are normally engaged by endogenous cannabinoid (endocannabinoid) substances. Outside the brain, THC...