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Sara R Westbrook

3 papers in the library · 2 citations · publishing 2024-2025

Papers

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Influence of Carrier Oil, Sex, and Age on Pharmacokinetic and Acute Behavioral Effects of Vaporized Cannabis Extract in Mice.

Cannabis and Cannabinoid Research December 1, 2025 Sara R Westbrook, Allison L Jensen, Vanessa Copeland-Solorzano et al. 2 citations

The legalization of cannabis in several states across the United States has increased the need to better understand its effects on the body, brain, and behavior, particularly in different populations. Previous rodent studies have revealed age and sex differences in response to injected Δ9-tetrahydrocannabinol (THC). However, the pharmacokinetic and pharmacodynamic properties of THC administered...

Sex Differences in Response-Contingent Cannabis Vapor Administration During Adolescence Mediate Enduring Effects on Behavioral Flexibility and Prefrontal Microglia Activation in Rats

Cannabis and Cannabinoid Research January 8, 2024 Timothy G. Freels, Sara R Westbrook, Erica Zamberletti et al.

Introduction: Cannabis is the most used illicit drug in the United States. With many states passing legislation to permit its recreational use, there is concern that cannabis use among adolescents could increase dramatically in the coming years. Historically, it has been difficult to model real-world cannabis use to investigate the causal relationship between cannabis use in adolescence and...

Influence of solvent, sex, and age on pharmacokinetic and acute behavioral effects of vaporized cannabis extract in mice

Sara R Westbrook, Allison L Jensen, Vanessa Copeland-Solorzano et al. preprint

Abstract The legalization of cannabis in several states across the US has increased the need to better understand its effects on the body, brain, and behavior, particularly in different populations. Rodent models are particularly valuable in this respect because they provide precise control over external variables. Previous rodent studies have found age and sex differences in response to...