Study on the Brain Metabolomic Changes of 4-HO-MiPT Infected Zebrafish by UHPLC-Q/Orbitrap HRMS
Zhipu Xuebao September 19, 2024 Yu-Bin Chen, Jiao-Yuan Yu, Liang Meng et al.
This study aimed to assess the neurotoxic effects of the novel psychoactive substance 4-hydroxy-N-methyl-N-isopropyltryptamine (4-HO-MiPT) on brain. By employing zebrafish as a model organism, the study applied a multifaceted approach, including the recording and analysis of spontaneous behavioral activities, identification of brain metabolic products via ultra-high performance liquid...