Biomed Pharmacother
March 19, 2026
Giulia Costa, Marcello Serra, Riccardo Maccioni et al.
correction
Corrigendum "Withania somnifera influences MDMA-induced hyperthermic, cognitive, neurotoxic and neuroinflammatory effects in mice." [Biomed. Pharmacother. 161 (2023) 114475].
Neural Regeneration Research
February 22, 2024
Marcello Serra, Nicola Simola, Alexia E Pollack et al.
19 citations
Preclinical and clinical studies indicate that psychostimulants, in addition to having abuse potential, may elicit brain dysfunctions and/or neurotoxic effects. Central toxicity induced by psychostimulants may pose serious health risks since the recreational use of these substances is on the rise among young people and adults. The present review provides an overview of recent research,...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
May 1, 2023
Giulia Costa, Marcello Serra, Riccardo Maccioni et al.
13 citations
Withania somnifera (WS) is utilized in Ayurvedic medicine owing to its central and peripheral beneficial properties. Several studies have accrued indicating that the recreational amphetamine-related drug (+/-)- 3,4-methylenedioxymethamphetamine (MDMA; Ecstasy) targets the nigrostriatal dopaminergic system in mice, inducing neurodegeneration and gliosis, causing acute hyperthermia and cognitive...
Neuropharmacology
2019
Giulia Costa, Marcello Serra, Nicholas Pintori et al.
&NA; Methoxetamine (MXE) is a novel psychoactive substance that can induce several short‐term effects on emotional states and behavior. However, little is known about the persistent emotional and behavioral effects of MXE. Moreover, neurotoxic effects of MXE have been hypothesized, but never demonstrated in vivo. To clarify these issues, rats received repeated treatment with MXE every other day...