MDMA (3, 4 Methylenedioxymethamphetamine) is a psychoactive drug under the amphetamine-type stimulant group. While the modulatory effects of MDMA on serotonin neurotransmission and its neurotoxicity in the central nervous system are well studied, MDMA’s effects on modulating microglial neuroimmune functions have attracted considerable attention. Resident glial cells, including microglia in the...