Psychedelic states offer a useful setting for studying changes in large-scale brain organization. Here, we applied Topological Data Analysis (TDA) to resting-state fMRI functional connectivity from nine participants scanned before and after Ayahuasca ingestion. Vietoris–Rips filtrations were constructed from correlation-derived dissimilarity matrices, and persistent entropy was used to quantify...
Qualia—the first-person qualities of subjective experiences that constitute the “what it is like”of phenomenal consciousness—have thus far resisted physical explanation. Here we hypothesizethat qualia are generated in the brain during the quantum computational resolution of difficultinverse problems when non-Clifford magic states are consumed above a threshold rate. Magicstates are a well-known...