Impact of psilocybin and Psilocybe cubensis extract on gut microbiota in Wistar Han rats
Science Letters April 17, 2026 Francisco Sacadura, Cláudia Marques, Andreia Machado Brito-Da-Costa et al.
Background: Psilocybin, the main psychoactive compound found in Psilocybe mushrooms, has gained increasing attention due to its potential therapeutic effects in neuropsychiatric disorders [1]. Beyond its central effects, increasing evidence highlights the relevance of the gut–brain axis, suggesting that psychedelics may also influence intestinal microbiota composition. Whole mushroom extracts...