Objective: Medical students experience high psychological demands that predispose them to stress, anxiety, and depression. This study aimed to determine the prevalence of stress, anxiety, and depression in 4th-year MBBS students and measure the efficacy of a short-term mindfulness-based life coaching (MBLC) intervention. Methods: This study consisted of a cross-sectional screening followed by a...
Psychedelic-assisted therapies have re-emerged as a subject of increasing scientific and clinical interest in psychiatry, particularly in the context of persistent treatment gaps for conditions such as treatment-resistant depression, post-traumatic stress disorder, and substance use disorders. Compounds, including psilocybin and 3,4-methylenedioxymethamphetamine, are being evaluated in...
New approaches to the neurobiology of posttraumatic stress disorder (PTSD) are needed to address the reported crisis in PTSD drug development. These new approaches may require the field to move beyond a narrow fear-based perspective, as fear-based medications have not yet demonstrated compelling efficacy. Antidepressants, particularly recent rapid-acting antidepressants, exert complex effects...