DESI-MSI-Based Multi-Organ Distribution Mapping of Psilocin in Zebrafish
Molecules June 18, 2026 Mengxuan Dong, Yi Zhang, Manzhu Cao et al.
Psilocybin, a psychedelic drug with reported anxiolytic and antidepressant potential, is rapidly metabolized to its active metabolite psilocin. However, a lack of adequate toxicity studies and tissue distribution studies currently restricts its development and application. This study combined behavioral assays in zebrafish with desorption electrospray ionization mass spectrometry imaging...