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Howard S. Lotsof

2 papers in the library · 385 citations · publishing 1999-2008

Papers

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The ibogaine medical subculture.

Journal of Ethnopharmacology January 4, 2008 Kenneth Alper, Howard S. Lotsof, Charles D. Kaplan 184 citations

Ibogaine is a naturally occurring psychoactive indole alkaloid that is used to treat substance-related disorders in a global medical subculture, and is of interest as an ethnopharmacological prototype for experimental investigation and possible rational pharmaceutical development. The subculture is also significant for risks due to the lack of clinical and pharmaceutical standards. This study...

Treatment of acute opioid withdrawal with ibogaine.

The American Journal on Addictions 1999 Kenneth Alper, Howard S. Lotsof, Geerte M. N. Frenken et al. 201 citations

Ibogaine is an alkaloid with putative effect in acute opioid withdrawal. Thirty-three cases of treatments for the indication of opioid detoxification performed in non-medical settings under open label conditions are summarized involving an average daily use of heroin of .64 +/- .50 grams, primarily by the intravenous route. Resolution of the signs of opioid withdrawal without further drug...