Age moderates the relationship between psychedelics use and mental health in naturalistic settings
Research Square March 10, 2026 Giammarco di Gregorio, Sophia Basset, Harjot Manmohan et al.
Abstract Depression and anxiety affect one in five adults, with age affecting prevalence. While clinical trials suggest classic psychedelics (e.g., psilocybin, LSD) and non-classic psychedelics (e.g., MDMA, ketamine) may alleviate these symptoms, it remains unclear how these relationships function in naturalistic settings or how they vary across the lifespan. We conducted a cross-sectional...