New Psychoactive Substance Esketamine Causes Endocrine-Disrupting Effects and Developmental Toxicity.
Environmental Science & Technology May 6, 2025 Si-Ying Li, Dongdong Ma, Wen-Jun Shi et al. 3 citations
Esketamine (ESK), a new psychoactive substance known for its strong hallucinogenic effect, has been detected in surface water worldwide. The toxicity of ESK to fish at a certain environmental concentration remains unclear. In this study, zebrafish embryos and ZF4 cells were exposed to ESK (0, 0.12, 1.02, and 10.6 μg L-1, marked by SC, LC, MC, and HC, respectively) for 14 days post fertilization...