Ketamine as an adjuvant to opioids for cancer pain
Cochrane Database of Systematic Reviews June 28, 2017 Rae Frances Bell, Christopher Eccleston, Eija Kalso 246 citations
BACKGROUND: This is an update of a review first published in 2003 and updated in 2012.Ketamine is a commonly used anaesthetic agent, and in subanaesthetic doses is also given as an adjuvant to opioids for the treatment of refractory cancer pain, when opioids alone or in combination with appropriate adjuvant analgesics prove to be ineffective. Ketamine is known to have psychomimetic (including...