Ketamine and postoperative pain – a quantitative systematic review of randomised trials
Pain December 15, 2004 Nadia Elia, Martin R. Tramèr 564 citations
Ketamine, an N-methyl-D-aspartate receptor antagonist, is known to be analgesic and to induce psychomimetic effects. Benefits and risks of ketamine for the control of postoperative pain are not well understood. We systematically searched for randomised comparisons of ketamine with inactive controls in surgical patients, reporting on pain outcomes, opioid sparing, and adverse effects. Data were...