Differential tolerance to biological and subjective effects of four closely spaced doses of N,N-dimethyltryptamine in humans
Biological Psychiatry May 1, 1996 Rick J. Strassman, Clifford Qualls, Laura M. Berg 129 citations
Tolerance of the behavioral effects of the short-acting, endogenous hallucinogen, N,N-dimethyltryptamine (DMT) is seen inconsistently in animals, and has not been produced in humans. The nature and time course of responses to repetitive, closely spaced administrations of an hallucinogenic dose of DMT were characterized. Thirteen experienced hallucinogen users received intravenous 0.3 mg/kg DMT...