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Loren L. Looger

1 paper in the library · 5 citations · publishing 2025

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Cortical Mechanisms Contributing to Ketamine-Induced Dissociation

The Neuroscientist December 26, 2025 Kallol Bera, Loren L. Looger, Alex Proekt et al. 5 citations

Ketamine is a unique anesthetic agent that induces dissociative anesthesia, characterized by perceptual detachment, analgesia, and altered states of consciousness. Beyond its widespread use in anesthesia, subhypnotic ketamine dosing has emerged as a rapid-acting antidepressant and a valuable model for probing the neural mechanisms underlying consciousness and neuropsychiatric disorders. At the...