Ketamine pharmacotherapy for major depressive disorder: A narrative review
Progress in Neuro-psychopharmacology and Biological Psychiatry February 27, 2026 Chris H. Miller, Angela Hickman, Caitlin Baten et al. 2 citations
Ketamine pharmacotherapy provides a novel treatment option for major depressive disorder (MDD) and has generated a large, growing body of research regarding its biochemical and clinical properties. This narrative review summarizes the history of ketamine's development, beginning as a general anesthetic, continuing with a discovery of its antidepressant properties, and leading up to its landmark...