ABSTRACT: Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist that has been approved for use as a clinical and veterinary anesthetic since 1970. Although esketamine, a specific molecular form of ketamine, is FDA-approved for the management of treatment-resistant depression, regular ketamine is often used off-label at subanesthetic doses to treat depression as well as other...
Abstract The concept of agency implies an active organism, one who desires, one who makes plans, carries out actions, and compares their actions to their desires. Such a concept of agency requires consciousness. There is little question that in adults, such conscious processes exist. The question is, from a developmental perspective when do they arise? In our work on the development of...