Ketamine and its Regulatory Implications: A Review
Journal of Medical Regulation December 1, 2025 Amol Soin, Y.c. Janardhan Reddy, Kris Ferguson et al.
ABSTRACT: Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist that has been approved for use as a clinical and veterinary anesthetic since 1970. Although esketamine, a specific molecular form of ketamine, is FDA-approved for the management of treatment-resistant depression, regular ketamine is often used off-label at subanesthetic doses to treat depression as well as other...