Advances and Challenges in LSD Detection: Analytical Techniques, Matrix Selection, and Validation Gaps in Forensic Toxicology
Critical Reviews in Analytical Chemistry November 4, 2025 Diksha Thakur, Neeti Prakash Dubey, Rajvinder Singh et al.
Lysergic acid diethylamide (LSD) remains a significant forensic and public health concern due to its widespread abuse and association with drug-facilitated crimes. Detecting LSD and its analogs in biological specimens, particularly postmortem matrices, presents analytical challenges stemming from its low dosage, rapid metabolism, and structural similarities to novel lysergamides. This review...