Yohei Sasaki

2 papers in the library · 20 citations · publishing 2010-2023

Papers

Peyote identification on the basis of differences in morphology, mescaline content, and trnL/trnF sequence between Lophophora williamsii and L. diffusa

Journal of Natural Medicines October 1, 2010 Masako Aragane, Yohei Sasaki, Jun’ichi Nakajima et al. 20 citations

The genus Lophophora includes two species: Lophophora williamsii (peyote) and L. diffusa. Contrary to earlier reports that L. williamsii contained mescaline and L. diffusa did not, some L. williamsii specimens lacked mescaline, showing that mescaline content alone cannot differentiate the species. The study examined morphology, mescaline content, and DNA sequences of the chloroplast trnL/trnF region. L. williamsii specimens fell into two groups: Group 1 had small epidermal protuberances, contained mescaline, and had an 881-base-pair (bp) DNA sequence (one exception at 877 bp); Group 2 had large protuberances, no mescaline, and a 893-bp sequence. L. diffusa had medium protuberances, no mescaline, and a 903-bp sequence. The PCR-RFLP method successfully distinguished the two species and differentiated the L. williamsii groups.

DOI: 10.1007/s11418-010-0469-7 Mescaline Morphology biology Anatomy Botany +1

Effectiveness of Mindfulness-Based Cognitive Therapy With Follow-Up Sessions for Pharmacotherapy-Refractory Anxiety Disorders: Protocol for a Feasibility Randomized Controlled Trial

JMIR Research Protocols August 28, 2023 Mitsuhiro Sado, Akira Ninomiya, Maki Nagaoka et al.

A feasibility randomized controlled trial compares augmented mindfulness-based cognitive therapy (MBCT) with follow-up sessions to augmented MBCT without follow-up sessions for adults aged 20–65 with panic disorder, agoraphobia, or social anxiety disorder that has not remitted after at least 4 weeks of usual treatment. The 8-week MBCT program includes a 10-month follow-up period. Primary outcomes are inclusion rate, dropout rate, attendance rate, and clinical measures at 8 weeks and 5, 8, and 12 months. Recruitment began in January 2020 and 43 participants were enrolled by January 2021; data collection is expected to finish by May 2022. The study is limited by mixed intervention delivery modes and lack of a pharmacotherapy-alone arm.

DOI: 10.2196/33776 Full text