Background: Results from contemporary clinical trials of serotonergic psychedelic therapies have led to an increasing focus on their potential clinical use across mental disorders. However, studies examining mechanisms of clinical response to psychedelic therapy in psychiatric populations are limited. This review aimed to synthesize evidence from studies examining biomarkers of clinical...
Abstract Humans have a long and complicated history with psychedelic compounds. Originally discovered as a component of certain plants and fungi, the psychedelics were widely used by ancient and indigenous peoples for millennia. Contemporary Western society had been largely disconnected from psychedelics but was reintroduced when Albert Hofmann first synthesized D-lysergic acid diethylamide...