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Orwa Dandash

4 papers in the library · 2 citations · publishing 2025-2026

Papers

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Impact of Psilocybin on Motor Function in Healthy Participants: A Phase 1, Randomised, Triple-Blind, Dose-Finding Study

CNS Drugs August 7, 2026 Chiranth Bhagavan, O. Carter, Glenn Nielsen et al.

BACKGROUND: Psychedelics exert widespread effects on brain activity, but their impact on motor function is unclear. This is clinically relevant given the emerging interest in psychedelic-assisted physical therapy for disorders of motor function. This study examined the feasibility and safety of administering movement tasks following low-to-moderate doses of psilocybin in healthy volunteers....

Sustained Effects of Low-to-Moderate Doses of Psilocybin on Brain Connectivity

medRxiv Preprint Server April 17, 2026 Chiranth Bhagavan, Orwa Dandash, Olivia Carter et al. preprint

Background Psilocybin is a classic psychedelic that acutely alters brain functional connectivity. These changes are linked to therapeutic doses and subjective effects, with some evidence that changes persist beyond acute drug administration. However, the effects of lower doses on sustained connectivity changes remain unclear.

Psychedelics in functional disorders: A scoping review

Progress in Neuro-psychopharmacology and Biological Psychiatry February 10, 2026 Chiranth Bhagavan, Olivia Carter, Alexander Bryson et al. 1 citation

Functional disorders, characterised by symptoms unexplained by organic disease, impose a significant burden on individuals and healthcare systems. Existing treatments are limited in efficacy, with no effective pharmacotherapies. There is growing evidence supporting the treatment potential of psychedelics in neuropsychiatric conditions, including several distinct functional disorders. This...

A Randomised, Triple-Blind, Dose-Finding Study of the Impact of Psilocybin on Motor Function in Healthy Participants

medRxiv December 23, 2025 Chiranth Bhagavan, Olivia Carter, Glenn Nielsen et al. 1 citation

Abstract Background Psychedelics exert widespread effects on brain activity, but their impact on motor function is unclear. This is clinically relevant given the emerging interest in psychedelic-assisted physical therapy for disorders of motor function. This study’s primary objectives examined the feasibility and safety of administering movement tasks following low-to-moderate doses of...