Dave Nichols

Faculty Opinions recommendation of Trial of Psilocybin versus Escitalopram for Depression.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature April 15, 2021 Dave Nichols

BACKGROUND: Psilocybin may have antidepressant properties, but direct comparisons between psilocybin and established treatments for depression are lacking.METHODS: In a phase 2, double-blind, randomized, controlled trial involving patients with long-standing, moderate-to-severe major depressive disorder, we compared psilocybin with escitalopram, a selective serotonin-reuptake inhibitor, over a...