7 papers in the library · 1,928 citations · publishing 2021-2024
EClinicalMedicine September 23, 2024 David Erritzøe, Tommaso Barba, Kyle T. Greenway et al. 46 citations
The Alexander Mosley Charitable Trust and by the founding partners of Imperial College London's Centre for Psychedelic Research.
Psychological Medicine 2024 Brandon Weiss, Induni Ginige, Lu Shannon et al. 38 citations
Psilocybin Therapy (PT) is being increasingly studied as a psychiatric intervention. Personality relates to mental health and can be used to probe the nature of PT's therapeutic action. In a phase 2, double-blind, randomized, active comparator controlled trial involving patients with moderate-to-severe major depressive disorder, we compared psilocybin with escitalopram, over a core 6-week trial...
Psychological Medicine July 19, 2023 Brandon Weiss, Induni Ginige, Lu Shannon et al. 1 citation
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Frontiers in Psychology May 11, 2023 Hannah Thurgur, Meg J. Spriggs, Ashleigh Murphy-Beiner et al. 13 citations
The field of psychedelic assisted therapy (PAT) is growing at an unprecedented pace. The immense pressures this places on those working in this burgeoning field have already begun to raise important questions about risk and responsibility. It is imperative that the development of an ethical and equitable infrastructure for psychedelic care is prioritized to support this rapid expansion of PAT...
Frontiers in Pharmacology March 31, 2022 Roberta Murphy, Roberta Murphy, Hannes Kettner et al. 229 citations
Background: Across psychotherapeutic frameworks, the strength of the therapeutic alliance has been found to correlate with treatment outcomes; however, its role has never been formally assessed in a trial of psychedelic-assisted therapy. We aimed to investigate the relationships between therapeutic alliance and rapport, the quality of the acute psychedelic experience and treatment outcomes....
Frontiers in Pharmacology March 31, 2022 Roberta Murphy, Roberta Murphy, Hannes Kettner et al. 229 citations
Background: Across psychotherapeutic frameworks, the strength of the therapeutic alliance has been found to correlate with treatment outcomes; however, its role has never been formally assessed in a trial of psychedelic-assisted therapy. We aimed to investigate the relationships between therapeutic alliance and rapport, the quality of the acute psychedelic experience and treatment outcomes....
New England Journal of Medicine April 14, 2021 Robin Carhart-Harris, Bruna Giribaldi, Rosalind Watts et al. 1,372 citations
On the basis of the change in depression scores on the QIDS-SR-16 at week 6, this trial did not show a significant difference in antidepressant effects between psilocybin and escitalopram in a selected group of patients. Secondary outcomes generally favored psilocybin over escitalopram, but the analyses of these outcomes lacked correction for multiple comparisons. Larger and longer trials are...