A dual-receptor model of serotonergic psychedelics
bioRxiv (Cold Spring Harbor Laboratory) April 15, 2024 Arthur Juliani, Veronica Chelu, Laura Graesser et al. 4 citations preprint
Abstract Serotonergic psychedelics have been identified as promising next-generation therapeutic agents in the treatment of mood and anxiety disorders. While their efficacy has been increasingly validated, the mechanism by which they exert a therapeutic effect is still debated. A popular theoretical account is that excessive 5-HT2a agonism disrupts cortical dynamics, relaxing the precision of...