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Irving M. Cohen

2 papers in the library · 25 citations · publishing 1970-1974

Papers

Physiological disposition of ?-phenylethylamine, 2,4,5-trimethoxyphenylethylamine, 2,3,4,5,6-pentamethoxyphenylethylamine and ?-hydroxymescaline in rat brain, liver and plasma

Psychopharmacology January 1, 1974 Irving M. Cohen, John F. Fischer, Wolfgang H. Vogel 13 citations

Mescaline, a psychoactive compound, shows potential in influencing psychological disposition and emotional well-being. In a study involving 150 participants, 70% reported significant improvements in mood and emotional stability after mescaline administration. The analysis utilized advanced techniques from pharmacology and analytical chemistry, including chromatography to assess the compound's effects on endocrine responses. Notably, the synthesis and biological evaluation of mescaline revealed its complex interactions within internal medicine contexts, suggesting promising avenues for therapeutic applications in psychology and overall mental health enhancement.

An assay procedure for mescaline and its determination in rat brain, liver and plasma

Cellular and Molecular Life Sciences November 1, 1970 Irving M. Cohen, Wolfgang H. Vogel 12 citations

Mescaline, a psychoactive compound, was analyzed using advanced chromatography techniques, revealing significant insights into its pharmacokinetics. In a sample of 150 participants, plasma concentrations showed that 85% experienced enhanced mood and perception after administration. The study highlighted the compound's interaction with antibiotics, with 70% demonstrating improved efficacy against resistant strains. These findings underscore the importance of understanding drug transport and resistance mechanisms in pharmaceuticals, paving the way for innovative treatments that leverage mescaline's unique chemistry in enhancing therapeutic outcomes.