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Nikolaus Seiler

1 paper in the library · 14 citations · publishing 1978

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3,4,5-Trimethoxybenzoic acid, a new mescaline metabolite in humans.

Drug Metabolism and Disposition September 1, 1978 Lothar Demisch, Peter Kaczmarczyk, Nikolaus Seiler 14 citations

After ingestion of 400 mg of mescaline sulfate by human volunteers, 3,4,5-trimethoxybenzoic acid was isolated from urine and identified by gas chromatography-mass spectrometry. The amount of this anionic mescaline metabolite was found to be very low as compared with that of the well-konwn 3,4,5-trimethoxyphenylacetic acid. The significance of this finding is discussed.