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René Royer

2 papers in the library · 7 citations · publishing 1986

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A versatile synthesis of 1-aryl-2-nitro-3-(3,4,5-trimethoxyphenyl)propenes as precursors of novel mescaline derivatives.

Chemical and Pharmaceutical Bulletin 1986 Daniel Dauzonne, René Royer 7 citations

A convenient one-step procedure to synthesize the title compounds (3a-v) by the reaction between 1, 2, 3-trimethoxy-5-(2-nitroethyl)benzene (1) and aromatic or heterocyclic aldehydes is reported. The obtained 1-aryl-2-nitro-3-(3, 4, 5-trimethoxyphenyl)propenes can easily be reduced to provide new mescaline derivatives. As an example, 1-(3-indolyl)-2-amino-3-(3, 4, 5-trimethoxyphenyl)propane...